Motif ID: RXRA_VDR{dimer}.p2

Z-value: 0.658


Transcription factors associated with RXRA_VDR{dimer}.p2:

Gene SymbolEntrez IDGene Name
VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
VDRchr12_-_48298765-0.647.2e-03Click!


Activity profile for motif RXRA_VDR{dimer}.p2.

activity profile for motif RXRA_VDR{dimer}.p2


Sorted Z-values histogram for motif RXRA_VDR{dimer}.p2

Sorted Z-values for motif RXRA_VDR{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRA_VDR{dimer}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_95047730 1.426 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr7_+_94536926 1.297 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr17_-_64225496 0.835 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_+_200993041 0.793


chr14_+_95047758 0.772 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr22_+_50624267 0.696 TRABD
TraB domain containing
chr10_+_102732285 0.688 NM_001203244
NM_017893
SEMA4G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

chr11_+_64863711 0.651 C11orf2
chromosome 11 open reading frame 2
chr11_+_64863700 0.650 C11orf2
chromosome 11 open reading frame 2
chr21_-_47575472 0.643 NM_006657
NM_206965
FTCD

formiminotransferase cyclodeaminase

chr11_+_64863607 0.619 NM_013265
C11orf2
chromosome 11 open reading frame 2
chr16_+_19078958 0.617 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr2_-_203735988 0.602 ICA1L
islet cell autoantigen 1,69kDa-like
chr1_+_100111430 0.556 NM_017734
PALMD
palmdelphin
chr17_-_7082654 0.523 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr19_-_7293876 0.499 NM_000208
NM_001079817
INSR

insulin receptor

chr22_+_50624353 0.490 NM_025204
TRABD
TraB domain containing
chrX_+_46940235 0.470 RGN
regucalcin (senescence marker protein-30)
chrX_+_153770458 0.461 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr13_-_76055872 0.451 NM_014832
TBC1D4
TBC1 domain family, member 4
chr2_-_203736223 0.447 NM_138468
ICA1L
islet cell autoantigen 1,69kDa-like
chr17_+_79935493 0.423 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr16_+_19079220 0.417 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr17_+_79935410 0.408 NM_001251888
NM_024083
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chr14_+_95047792 0.398 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr17_-_34756980 0.395 NM_001123392
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3H
chr16_+_19078916 0.387 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr18_-_6414900 0.383 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr2_+_108905094 0.377 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr17_+_36283959 0.370 NM_001123391
NM_032258
TBC1D3C
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr17_-_36348585 0.358 NM_001123391
NM_032258
TBC1D3C
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr17_-_34503914 0.345 NM_001001417
TBC1D3B
TBC1D3C
TBC1D3G
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
chr5_-_32174327 0.343 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr10_+_80899458 0.340 ZMIZ1
zinc finger, MIZ-type containing 1
chr17_-_34591958 0.337 NM_001001418
TBC1D3C
TBC1D3G
TBC1 domain family, member 3C
TBC1 domain family, member 3G
chr20_+_37590969 0.334 NM_001190809
NM_021931
DHX35

DEAH (Asp-Glu-Ala-His) box polypeptide 35

chr21_-_46340821 0.332 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr14_-_35873823 0.331 NM_020529
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr19_-_9731883 0.321 NM_152289
ZNF561
zinc finger protein 561
chr5_-_32174397 0.321 NM_022130
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr7_-_95025622 0.318 NM_000940
PON3
paraoxonase 3
chr21_+_40177754 0.314 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr3_-_49142165 0.309 NM_005051
QARS
glutaminyl-tRNA synthetase
chr2_+_20646831 0.302 NM_004040
RHOB
ras homolog gene family, member B
chr5_-_32174385 0.296 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr16_+_14726828 0.288 BFAR
bifunctional apoptosis regulator
chr5_-_32174355 0.288 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr16_+_57392694 0.285 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr17_+_18380097 0.280 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr17_+_77893155 0.279


chr21_+_46825001 0.265 NM_130445
COL18A1
collagen, type XVIII, alpha 1
chr5_-_32174242 0.263 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr11_+_128563772 0.262 NM_001167681
NM_002017
FLI1

Friend leukemia virus integration 1

chr9_-_5833072 0.262 NM_024896
ERMP1
endoplasmic reticulum metallopeptidase 1
chr14_-_94856926 0.258 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr1_+_229406835 0.255 NM_004578
RAB4A
RAB4A, member RAS oncogene family
chr22_+_18593556 0.254 TUBA8
tubulin, alpha 8
chr21_+_40177847 0.252 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr19_+_45409003 0.250 NM_000041
APOE
apolipoprotein E
chr1_+_203764802 0.231 ZC3H11A
zinc finger CCCH-type containing 11A
chr21_-_46340776 0.231 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr19_-_44008984 0.230 NM_198850
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr9_-_5832840 0.229 ERMP1
endoplasmic reticulum metallopeptidase 1
chr20_+_47538211 0.225 NM_006420
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr19_-_42759279 0.220 NM_006494
ERF
Ets2 repressor factor
chr2_+_230787195 0.218 NM_174899
FBXO36
F-box protein 36
chr17_-_20370819 0.218 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr1_+_203764822 0.215 ZC3H11A
zinc finger CCCH-type containing 11A
chr2_-_39664291 0.213 MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr20_+_34680569 0.212 EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr22_+_23134980 0.211


chr11_+_36616039 0.210 NM_138787
C11orf74
chromosome 11 open reading frame 74
chr1_-_46152183 0.210 NM_021639
GPBP1L1
GC-rich promoter binding protein 1-like 1
chr14_+_105780751 0.198 NM_001100913
NM_015197
PACS2

phosphofurin acidic cluster sorting protein 2

chr10_+_30723050 0.197 MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr18_-_7117757 0.192 NM_005559
LAMA1
laminin, alpha 1
chr11_+_66278076 0.189 NM_024649
BBS1
Bardet-Biedl syndrome 1
chr19_+_10791025 0.187


chr3_-_54961961 0.185 NM_020678
LRTM1
leucine-rich repeats and transmembrane domains 1
chr19_+_39899749 0.184


chr20_+_389346 0.180 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr1_+_203764750 0.177 NM_014827
ZC3H11A
zinc finger CCCH-type containing 11A
chr11_+_7535213 0.175 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_-_42759151 0.169 ERF
Ets2 repressor factor
chr21_+_46825291 0.167


chr7_+_128577990 0.164 NM_001098629
NM_001098630
NM_001242452
IRF5


interferon regulatory factor 5


chr19_-_460995 0.162 NM_012435
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr19_+_35531409 0.161 NM_002151
NM_182983
HPN

hepsin

chr16_-_3767449 0.159 NM_016292
TRAP1
TNF receptor-associated protein 1
chr19_+_1941184 0.159 CSNK1G2
casein kinase 1, gamma 2
chr19_+_50270263 0.155 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr6_-_132272311 0.151 NM_001901
CTGF
connective tissue growth factor
chr7_+_39989955 0.150 NM_003718
NM_031267
CDK13

cyclin-dependent kinase 13

chr18_-_32924381 0.150 ZNF24
zinc finger protein 24
chr6_+_151646634 0.149 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr8_-_93115453 0.146 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr4_-_2757750 0.146 NM_001161527
TNIP2
TNFAIP3 interacting protein 2
chr2_+_33738941 0.146 NM_015376
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr16_-_89768094 0.145 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr12_+_70172748 0.145 NM_001024647
RAB3IP
RAB3A interacting protein (rabin3)
chr14_+_58765209 0.143 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr17_+_72462780 0.143 CD300A
CD300a molecule
chr16_+_14726667 0.142 NM_016561
BFAR
bifunctional apoptosis regulator
chr7_+_128578246 0.141 NM_032643
IRF5
interferon regulatory factor 5
chr4_+_1902352 0.140 NM_133334
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr3_+_12392993 0.140 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr1_+_110527701 0.139 AHCYL1
adenosylhomocysteinase-like 1
chr10_+_111767877 0.139 ADD3
adducin 3 (gamma)
chr3_-_196159272 0.138 UBXN7
UBX domain protein 7
chr18_-_32924417 0.137 NM_006965
ZNF24
zinc finger protein 24
chr6_-_7910716 0.137 NM_030810
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr19_+_1941157 0.137 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chrX_-_40036581 0.134 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr1_+_226016428 0.131 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr14_-_35591652 0.130 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr10_+_35484829 0.129 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr13_+_24844846 0.128 SPATA13
spermatogenesis associated 13
chr14_-_35591151 0.121 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr6_+_31802644 0.121 NM_001040437
NM_001040438
C6orf48

chromosome 6 open reading frame 48

chr3_-_149470254 0.121 NM_016094
COMMD2
COMM domain containing 2
chr6_-_7910278 0.119 NM_001145549
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr7_-_91764036 0.117 NM_001146152
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr19_+_13056656 0.116 RAD23A
RAD23 homolog A (S. cerevisiae)
chr14_+_58765275 0.116 ARID4A
AT rich interactive domain 4A (RBP1-like)
chr12_+_57610577 0.114 NM_007224
NXPH4
neurexophilin 4
chr22_+_46692637 0.113 NM_016426
GTSE1
G-2 and S-phase expressed 1
chr20_-_52790511 0.110 NM_000782
NM_001128915
CYP24A1

cytochrome P450, family 24, subfamily A, polypeptide 1

chr19_+_13056607 0.109 NM_005053
RAD23A
RAD23 homolog A (S. cerevisiae)
chr9_+_35673852 0.107 NM_001216
CA9
carbonic anhydrase IX
chr16_+_16043206 0.107 NM_004996
NM_019862
NM_019898
NM_019899
NM_019900
ABCC1




ATP-binding cassette, sub-family C (CFTR/MRP), member 1




chr5_-_63257545 0.105 NM_000524
HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr1_+_87794150 0.104 NM_006769
LMO4
LIM domain only 4
chr3_-_196159296 0.104 UBXN7
UBX domain protein 7
chr22_+_45705965 0.104 FAM118A
family with sequence similarity 118, member A
chr15_+_75074714 0.103 CSK
c-src tyrosine kinase
chr11_-_74022609 0.101 NM_182904
P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr19_-_47987475 0.101 NM_007059
KPTN
kaptin (actin binding protein)
chr20_+_3801164 0.101 NM_001204446
NM_001204447
NM_018347
C20orf29


chromosome 20 open reading frame 29


chr11_-_77791264 0.100 NM_001203260
NM_001203261
NM_001203262
NM_001204054
NM_001204055
NM_004549
NDUFC2-KCTD14


NDUFC2


NDUFC2-KCTD14 readthrough


NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa


chr11_+_63997752 0.100 NM_005528
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr6_+_35227478 0.098 NM_003427
ZNF76
zinc finger protein 76
chr22_+_45705766 0.098 NM_017911
FAM118A
family with sequence similarity 118, member A
chr5_-_63257959 0.098 HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr1_-_175712669 0.097 NM_003285
TNR
tenascin R (restrictin, janusin)
chr17_-_43487747 0.096 ARHGAP27
Rho GTPase activating protein 27
chr11_+_17298278 0.096 NM_005013
NUCB2
nucleobindin 2
chr1_-_183559669 0.095 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr17_+_47653474 0.095 NXPH3
neurexophilin 3
chr19_+_56186426 0.095 NM_001130072
NM_013333
EPN1

epsin 1

chr17_-_76778306 0.092 NM_004762
NM_017456
CYTH1

cytohesin 1

chr15_+_83776323 0.090 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr11_+_60223281 0.090 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr8_+_87354958 0.089 NM_007013
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr3_-_13057130 0.089


chr3_-_196159304 0.084 NM_015562
UBXN7
UBX domain protein 7
chr19_+_13056671 0.084 RAD23A
RAD23 homolog A (S. cerevisiae)
chr22_+_39916563 0.083 NM_001675
NM_182810
ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

chr14_-_106494166 0.082 IGHV4-31
IGHA1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
chr11_-_60719116 0.082 NM_016582
SLC15A3
solute carrier family 15, member 3
chr1_-_235812994 0.082 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr1_+_151043079 0.081 NM_144618
GABPB2
GA binding protein transcription factor, beta subunit 2
chr3_+_38032260 0.080 VILL
villin-like
chr14_-_34419957 0.078 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr1_+_226736500 0.078 NM_001003665
C1orf95
chromosome 1 open reading frame 95
chr4_-_122302112 0.078 NM_198179
QRFPR
pyroglutamylated RFamide peptide receptor
chr15_+_50474357 0.076 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr19_-_4559713 0.075 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr11_+_124609841 0.074 NRGN
neurogranin (protein kinase C substrate, RC3)
chr15_-_75230354 0.074 COX5A
cytochrome c oxidase subunit Va
chr16_-_31106125 0.073 NM_024006
NM_206824
VKORC1

vitamin K epoxide reductase complex, subunit 1

chr5_-_147211141 0.073 SPINK1
serine peptidase inhibitor, Kazal type 1
chr20_+_39765849 0.071 PLCG1
phospholipase C, gamma 1
chr1_-_45140117 0.071 TMEM53
transmembrane protein 53
chr15_+_91428271 0.070 NM_001143783
NM_001143784
FES

feline sarcoma oncogene

chr15_+_69452799 0.070 NM_015554
GLCE
glucuronic acid epimerase
chr2_+_220363536 0.070 NM_013335
NM_205847
GMPPA

GDP-mannose pyrophosphorylase A

chr15_-_75230386 0.070 NM_004255
COX5A
cytochrome c oxidase subunit Va
chr1_-_40157067 0.069 NM_016257
HPCAL4
hippocalcin like 4
chr17_+_7123149 0.069 NM_000018
NM_001033859
ACADVL

acyl-CoA dehydrogenase, very long chain

chr17_+_65373923 0.069 NM_012417
NM_181671
PITPNC1

phosphatidylinositol transfer protein, cytoplasmic 1

chr4_+_144434555 0.067 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr3_+_52529370 0.067 STAB1
stabilin 1
chr12_+_113659275 0.065 TPCN1
two pore segment channel 1
chr11_-_63536112 0.065 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr19_-_12444435 0.065 NM_145276
ZNF563
zinc finger protein 563
chr11_+_46639112 0.065 ATG13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr18_-_74844710 0.064 MBP
myelin basic protein
chr20_+_30697291 0.063 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr1_-_45140062 0.061 NM_024587
TMEM53
transmembrane protein 53
chr6_-_79787887 0.061 PHIP
pleckstrin homology domain interacting protein
chr14_+_23790671 0.060 PABPN1
poly(A) binding protein, nuclear 1
chr5_-_179233624 0.060 MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr10_-_22292362 0.059 DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr6_-_32145841 0.059 NM_032741
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr6_-_79787784 0.059 PHIP
pleckstrin homology domain interacting protein
chr1_-_27732069 0.058 WASF2
WAS protein family, member 2
chr19_+_7985884 0.058 SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr16_-_31106049 0.058 VKORC1
vitamin K epoxide reductase complex, subunit 1
chr3_-_14988939 0.058 LOC100505641
uncharacterized LOC100505641
chr12_+_113659216 0.058 NM_001143819
NM_017901
TPCN1

two pore segment channel 1


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.